A Highly Regioselective Salt-Free Iron-Catalyzed Allylic Alkylation

摘要

Transition-metal-catalyzed reactions belong to the most important tools in synthetic organic chemistry. Over the past 30 years the productive collaboration between organic and inorganic chemists has led to a dynamic evolution in this field and, as a consequence, to the development of a variety of new transformations. Apart from the invention of new reactions, the use of only small amounts of a catalyst is advantageous with regard to environmental aspects. Although the amount of catalyst employed is usually very low the high price of these compounds often prevents their application on a large scale. Hence, the search for new catalysts based on inexpensive nontoxic metals such as iron has gained increasing attention in the past years.