Ligand‐Controlled Direct γ‐C?H Arylation of Aldehydes

Li Bijin; Lawrence Brianna; Li Guigen; Ge Haibo

摘要

Abstract > The first example of Pd II ‐catalyzed γ‐C(sp 3 )?H functionalization of aliphatic and benzoheteroaryl aldehydes has been developed using a transient ligand and an external ligand, concurrently. A wide array of γ‐arylated aldehydes were readily accessed without preinstalling internal directing groups. The catalytic mechanism was studied by performing deuterium‐labelling experiments, which indicated that the γ‐C(sp 3 )?H bond cleavage is the rate‐limiting step during the reaction process. This reaction could be performed on a gram scale, and also demonstrated its potential application in the synthesis of new mechanofluorochromic materials with blue‐shifted mechanochromic properties. </abstract> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> <div class="translation abstracttxt"> <span class="zhankaihshouqi fivelineshidden" id="abstract"> <span>机译：</span><Abstract Type =“Main”XML：Lang =“en”> <标题类型=“main”>抽象</ title> > PD的第一个例子 ii </ sup> - 催化γ-C（SP 3 </ sup> ）（同时使用瞬时配体和外部配体开发出脂族和苯甲酸甲酰胺醛醛的H官能化。容易进入各种γ-芳族化醛而无需预先安装内部引导基团。通过进行氘标记实验研究催化机制，表明γ-C（SP 3 </ sup> ）？H键切割是反应过程中的速率限制步骤。该反应可以对克垢进行进行，并且还证明了其在具有蓝移部机械光学变量性质的新机械荧光体材料的合成中的潜在应用。 </ p> </摘要> </span> <span class="z_kbtn z_kbtnclass hoverxs" style="display: none;">展开▼</span> </div> </div> <div class="record"> <h2 class="all_title" id="enpatent33" >著录项</h2> <ul> <li> <span class="lefttit">来源</span> <div style="width: 86%;vertical-align: text-top;display: inline-block;"> <a href='/journal-foreign-19011/'>《Angewandte Chemie》</a> <b style="margin: 0 2px;">|</b><span>2020年第8期</span><b style="margin: 0 2px;">|</b><span>共5页</span> </div> </li> <li> <div class="author"> <span class="lefttit">作者</span> <p id="fAuthorthree" class="threelineshidden zhankaihshouqi"> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Bijin&option=202" target="_blank" rel="nofollow">Li Bijin;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lawrence Brianna&option=202" target="_blank" rel="nofollow">Lawrence Brianna;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Guigen&option=202" target="_blank" rel="nofollow">Li Guigen;</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Ge Haibo&option=202" target="_blank" rel="nofollow">Ge Haibo;</a> </p> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zkzz" style="display: none;">展开▼</span> </div> </li> <li> <div style="display: flex;"> <span class="lefttit">作者单位</span> <div style="position: relative;margin-left: 3px;max-width: 639px;"> <div class="threelineshidden zhankaihshouqi" id="fOrgthree"> <p>Department of Chemistry and Chemical BiologyIndiana University-Purdue University IndianapolisIndianapolis Indiana 46202 USA;</p> <p>Department of Chemistry and Chemical BiologyIndiana University-Purdue University IndianapolisIndianapolis Indiana 46202 USA;</p> <p>Institute of Chemistry &</p> <p>BioMedical SciencesNanjing UniversityNanjing 210093 P. R. China;</p> <p>Department of Chemistry and Chemical BiologyIndiana University-Purdue University IndianapolisIndianapolis Indiana 46202 USA;</p> </div> <span class="z_kbtnclass z_kbtnclassall hoverxs" id="zhdw" style="display: none;">展开▼</span> </div> </div> </li> <li > <span class="lefttit">收录信息</span> <span style="width: 86%;vertical-align: text-top;display: inline-block;"></span> </li> <li> <span class="lefttit">原文格式</span> <span>PDF</span> </li> <li> <span class="lefttit">正文语种</span> <span>eng</span> </li> <li> <span class="lefttit">中图分类</span> <span><a href="https://www.zhangqiaokeyan.com/clc/1188.html" title="应用化学">应用化学;</a></span> </li> <li class="antistop"> <span class="lefttit">关键词</span> <p style="width: 86%;vertical-align: text-top;"> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=aldehydes&option=203" rel="nofollow">aldehydes;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=C?H activation&option=203" rel="nofollow">C?H activation;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=mechanochromism&option=203" rel="nofollow">mechanochromism;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=palladium&option=203" rel="nofollow">palladium;</a> <a style="color: #3E7FEB;" href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=reaction mechanisms&option=203" rel="nofollow">reaction mechanisms;</a> </p> <div class="translation"> 机译：醛;C？H激活;机械光学变色;钯;反应机制; </div> </li> </ul> </div> </div> <div class="literature cardcommon"> <div class="similarity "> <h3 class="all_title" id="enpatent66">相似文献</h3> <div class="similaritytab clearfix"> <ul> <li class="active" >外文文献</li> <li >中文文献</li> <li >专利</li> </ul> </div> <div class="similarity_details"> <ul > <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704028160983.html">Ligand‐Controlled Direct γ‐C?H Arylation of Aldehydes</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Bijin&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Li Bijin,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Lawrence Brianna&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Lawrence Brianna,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Li Guigen&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Li Guigen,</a> <a href="/journal-foreign-19011/" target="_blank" rel="nofollow" class="tuijian_authcolor">Angewandte Chemie .</a> <span>2020</span><span>,第8期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：配体控制的直接γ-C？H芳族化醛</span> </p> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704018500083.html">Pd(OAc)(2)/AgOAc Catalytic System Based Bidentate Ligand Directed Regiocontrolled C-H Arylation and Alkylation of the C-3 Position of Thiophene- and Furan-2-carboxamides</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Padmavathi Rayavarapu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Padmavathi Rayavarapu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Sankar Rathinam&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Sankar Rathinam,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Gopalakrishnan Bojan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Gopalakrishnan Bojan,</a> <a href="/journal-foreign-23259/" target="_blank" rel="nofollow" class="tuijian_authcolor">European journal of organic chemistry .</a> <span>2015</span><span>,第17期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：基于Pd（OAc）（2）/ AgOAc的双齿配体定向区域控制的C-H芳基化反应和噻吩和呋喃-2-羧酰胺的C-3位置烷基化</span> </p> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/journal-foreign-detail/0704019015783.html">Ligand-controlled chemoselectivity in potassium tert-amylate-promoted direct C-H arylation of unactivated benzene with aryl halides</a> <b>[J]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Liu Wei&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Liu Wei,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xu Lige&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Xu Lige </a> <a href="/journal-foreign-30440/" target="_blank" rel="nofollow" class="tuijian_authcolor">Tetrahedron .</a> <span>2015</span><span>,第30期</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：叔戊酸钾促进未活化苯与芳基卤化物直接C-H芳基化中配体控制的化学选择性</span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-conference-foreign_meeting-252588_thesis/0705010370579.html">Catalytic Asymmetric Arylation of Aldehydes by Using Grignard Reagents</a> <b>[C]</b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Yusuke Muramatsu&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Yusuke Muramatsu,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Toshiro Harada&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Toshiro Harada </a> <a href="/conference-foreign-252588/" target="_blank" rel="nofollow" class="tuijian_authcolor">Symposium on Organometallic Chemistry .</a> <span>2008</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：使用格氏试剂催化醛的催化不对称芳族化</span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-degree-foreign_mphd_thesis/02061300788.html">I. Multicatalysis: Development of a Bismuth(III) triflate-catalyzed Nucleophilic addition/ Hydrofunctionalization Reaction in the Synthesis of Complex Heterocycles II. C--H Arylation of Arenes and Heteroarenes with Palladium-Carboxylate Catalysts: Identification of the Catalyst Resting State and the Crucial Role of Pivalate Ligand in Stabilization of the Catalyst III. C--H Arylation of Heteroarenes with Palladium-Carboxylate Catalysts: Importance of Phosphine Ligand for Basic Heteroarene Substrates IV. C--H Arylation of Heteroarenes with Palladium-Carboxylate Catalysts: Effect of the Properties of Basic Heteroarene Substrates on Direct Arylations.</a> <b>[D] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Tundel, Rachel E.&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Tundel, Rachel E. </a> <span>2011</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：I.多催化作用：在复杂的杂环化合物的合成中三氟甲磺酸铋（III）催化的亲核加成/加氢官能化反应的发展。羰基钯催化剂对芳烃和杂芳烃的CH-H芳基化反应：催化剂静止状态的鉴定以及新戊酸酯配体在稳定催化剂中的关键作用III。羰基钯催化剂催化杂芳烃的CH芳基化：膦配体对基础杂芳烃基质的重要性IV。杂芳烃与钯-羧酸酯的CH芳基化：碱性杂芳烃底物性能对直接芳基化的影响。</span> </p> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-journal-foreign-pmc_detail_thesis/040005321537.html">Direct Aldehyde C–H Arylation and Alkylation via the Combination of Nickel HAT and Photoredox Catalysis</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Xiaheng Zhang&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Xiaheng Zhang,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=David W. C. MacMillan&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">David W. C. MacMillan </a> <span>-1</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过镍HAT和光氧化还原催化的直接乙醛CH-H酰化和烷基化</span> </p> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/open-access_resources_thesis/01000125922396.html">Ligand‐Controlled Direct γ‐C−H Arylation of Aldehydes</a> <b>[O] </b> . <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Bijin Li&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Bijin Li,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Brianna Lawrence&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Brianna Lawrence,</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Guigen Li&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">Guigen Li,</a> <span>2020</span> </span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：醛的配体控制的直接γ-C-H芳族化</span> </p> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/academic-journal-cn_petrochemical-translation-bundle_thesis/0201262949343.html">芳族羧酸加氢制芳族醛的技术开发及工业化</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=横山寿治&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 横山寿治</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=朴明福&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,朴明福</a> <span> <a href="/journal-cn-42502/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 石油化工译丛 </a> </span> <span> . 1992</span><span>,第001期</span> </span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chemical-translation-bundle_thesis/0201263155922.html">通过控制硝化直接从苯及其衍生物联产芳族一元胺和芳族二元胺（上）</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王睿&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 王睿</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=许树松&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,许树松</a> <span> <a href="/journal-cn-40709/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 化工译丛 </a> </span> <span> . 2004</span><span>,第003期</span> </span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/academic-journal-cn_chinese-journal-catalysis_thesis/0201231571824.html">采用燃烧技术制备Cuo纳米粒子:一种高效且环境友好的用于芳族醛合成芳族腈催化剂</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Belladamadu Siddappa ANANDAKUMAR&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . Belladamadu Siddappa ANANDAKUMAR</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Muthukur Bhojegowd Madhusudana REDDY&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Muthukur Bhojegowd Madhusudana REDDY</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=Chikka Nagaiah THARAMANI&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,Chikka Nagaiah THARAMANI</a> <span> <a href="/journal-cn-28399/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 催化学报 </a> </span> <span> . 2013</span><span>,第004期</span> </span> </div> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/academic-journal-cn_foreign-technology_thesis/0201262976832.html">用芳酸直接氢化制芳醛的新方法</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=陈丽娟&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 陈丽娟</a> <span> <a href="/journal-cn-42507/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 国外科技 </a> </span> <span> . 1991</span><span>,第007期</span> </span> </div> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/academic-journal-cn_detail_thesis/0201296798263.html">含硫Schiff碱型配体的合成研究——芳醛缩-4-烯丙基-3-硫代氨基脲的合成与表征</a> <b>[J]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=赵明根&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 赵明根</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=范建凤&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,范建凤</a> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=李志英&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor">,李志英</a> <span> <a href="/journal-cn-57029/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 化学试剂 </a> </span> <span> . 2003</span><span>,第6期</span> </span> </div> </li> <li> <div> <b>6. </b><a class="enjiyixqcontent" href="/academic-conference-cn_meeting-58479_thesis/020222885080.html">微机SCR全数字化直接相位控制与增量式模糊自适应控制</a> <b>[C]</b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=王祥国&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 王祥国</a> <span> <a href="/conference-cn-58479/" target="_blank" rel="nofollow" class="tuijian_authcolor"> . 控制理论及其应用年会 </a> <span> <span> . 1991</span> </span> </div> </li> <li> <div> <b>7. </b><a class="enjiyixqcontent" href="/academic-degree-domestic_mphd_thesis/020311564364.html">(S)-BINOL-Ti配体催化的部分钝化的芳乙基格氏试剂对醛的不对称加成反应研究</a> <b>[A] </b> <span> <a href="/search.html?doctypes=4_5_6_1-0_4-0_1_2_3_7_9&sertext=刘义&option=202" target="_blank" rel="nofollow" class="tuijian_auth tuijian_authcolor"> . 刘义</a> <span> . 2009</span> </span> </div> </li> </ul> <ul style="display: none;"> <li> <div> <b>1. </b><a class="enjiyixqcontent" href="/patent-detail/06120105061190.html">氧化含有烷基取代基的芳族化合物的方法,制备芳族醛化合物的方法,以及制备芳族羧酸酯的方法</a> <b>[P]</b> . <span> 中国专利： CN1863757A </span> <span> . 2006-11-15</span> </div> </li> <li> <div> <b>2. </b><a class="enjiyixqcontent" href="/patent-detail/061204142000.html">基于芳族醛和芳族多酚的具有高流动性水平的橡胶组合物</a> <b>[P]</b> . <span> 中国专利： CN108431130B </span> <span> . 2020.12.08</span> </div> </li> <li> <div> <b>3. </b><a class="enjiyixqcontent" href="/patent-detail/06130414484484.html">LIGAND-CONTROLLED C(SP3)-H ARYLATION AND OLEFINATION IN SYNTHESIS OF UNNATURAL CHIRAL ALPHA AMINO ACIDS</a> <b>[P]</b> . <span> 外国专利：  WO2015131100A1 </span> <span> . 2015-09-03</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：配体控制的C（SP3）-H芳基化和不饱和合成非手性手性氨基酸 </span> </p> </li> <li> <div> <b>4. </b><a class="enjiyixqcontent" href="/patent-detail/06130401233018.html">CONTROLLING THE NORMAL:ISO ALDEHYDE RATIO IN A MIXED LIGAND HYDROFORMYLATION PROCESS BY CONTROLLING THE SYNGAS PARTIAL PRESSURE</a> <b>[P]</b> . <span> 外国专利：  PL2516372T5 </span> <span> . 2020-08-10</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过控制SYNGAS分压来控制混合配体加氢甲酰化过程中的正乙醛比例 </span> </p> </li> <li> <div> <b>5. </b><a class="enjiyixqcontent" href="/patent-detail/06130403865294.html">CONTROLLING THE NORMAL:ISO ALDEHYDE RATIO IN A MIXED LIGAND HYDROFORMYLATION PROCESS BY CONTROLLING THE SYNGAS PARTIAL PRESSURE.</a> <b>[P]</b> . <span> 外国专利：  MX365495B </span> <span> . 2019-06-05</span> </div> <p class="zwjiyix translation" style="max-width: initial;height: auto;word-break: break-all;white-space: initial;text-overflow: initial;overflow: initial;"> <span>机译：通过控制符号分压来控制混合配体加氢甲酰化过程中的正乙醛比例。 </span> </p> </li> </ul> </div> </div> </div> <div class="theme cardcommon" style="overflow: auto;display:none"> <h3 class="all_title" id="enpatent55">相关主题</h3> <ul id="subject"> </ul> </div> </div> </div> </div> <div class="right rightcon"> <div class="details_img cardcommon clearfix" style="margin-bottom: 10px;display:none;" > </div> </div> </div> <div id="thesis_get_original1" class="downloadBth" style="bottom: 19px;z-index: 999;" onclick="ywcd('0704028160983','4',7,2,1,'',this,24)" class="delivery" prompt="010401" title="通过人工服务将文献原文发送至邮箱" >获取原文</div> <div class="journalsub-pop-up" style="display: none"> <div class="journal-sub"> <h2>期刊订阅</h2> <img src="https://cdn.zhangqiaokeyan.com/img/loginclose.png" alt="关闭" onclick="$('.journalsub-pop-up').hide()"> <p class="pardon">抱歉，该期刊暂不可订阅，敬请期待！</p> <p class="current">目前支持订阅全部北京大学中文核心（2020）期刊目录。</p> <div style="display: flex;margin-top: 69px;justify-content: space-between;"> <div class="no-sub" onclick="$('.journalsub-pop-up').hide()">暂不订阅</div> <div class="other-sub" onclick="continueSub('from=pc-detail')">继续订阅其他期刊</div> </div> </div> </div> <div class="right_btn"> <ul> <li class="gouwuche">  </li> <li class="yijian"> <a href="javascript:void(0);" onclick="link_analysis('/mycenter/auth/complaint.html',this)" title="意见反馈">意见反馈</a> </li> <li class="top"> <a href="javascript:scrollTo(0,0);" title="回到顶部">回到顶部</a> </li> <li class="shouye"> <a href="/" title="首页">回到首页</a> </li> </ul> </div> <div class="xllindexfooter"> <div class="xllindexfootercenter"> <div class="xllindexfooterleft left" > <div class="xllindexfooterleftli"> <ul> <li><a href="/about.html" title="关于掌桥">关于掌桥</a></li> <li><a href="/help/helpmap.html" title="资源导航">资源导航</a></li> <li><a href="/help/helpguide.html" title="新手指南">新手指南</a></li> <li><a href="/help/helpcenter.html" title="常见问题">常见问题</a></li> <li><a href="/sitemap.html" title="网站地图">网站地图</a></li> <li><a href="/help/helpcenter.html?type=9" title="版权声明">版权声明</a></li> </ul> </div> <div class="xllindexfooterleft"> <p class="xllindexfooterlefteamil">客服邮箱：kefu@zhangqiaokeyan.com</p> <div class="xllindexfooterlefttcp"> <div class="xllindexfooterpoliceiimg"></div> <div class="xllindexfooterpoliceispan"> <span>京公网安备：11010802029741号 </span> <span>ICP备案号：<a href="https://beian.miit.gov.cn" rel="nofollow" target="_blank" title="ICP备案号">京ICP备15016152号-6</a></span> <span>六维联合信息科技 (北京) 有限公司©版权所有</span> </div> </div> </div> </div> <div class="xllindexfooterright left"> <ul> <li> <p style="font-weight: bold;">客服微信</p> <div></div> </li> <li> <p style="font-weight: bold;">服务号</p> <div></div> </li> </ul> </div> </div> </div> <span id="0704028160983down" data-source="7," data-out-id="hHVyx0xHip9m1P0m5OPpg3cDljm8WPt4Dex1Z+itDj/upSxnY5cEEmlg5wIONtAu," data-f-source-id="7" data-title="Ligand‐Controlled Direct γ‐C?H Arylation of Aldehydes" data-price="20" data-site-name="" data-transnum="24" style="display:none;"></span> <input type="hidden" value="4" id="sourcetype"> <input type="hidden" value="19011" id="journalid"> <input type="hidden" value="1" id="inyn_provide_service_level"> <input type="hidden" value="https://cdn.zhangqiaokeyan.com" id="imgcdn"> <input type="hidden" value="1" id="isdeatail"> <input type="hidden" value="" id="syyn_indexed_database"> <input type="hidden" value="" id="servicetype"> <input type="hidden" id="pagename" value="Ligand‐Controlled Direct γ‐C?H Arylation of Aldehydes"/> <input type="hidden" value="thesis_get_original" id="pageIdentification"> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/jquery-1.12.4.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/lwlh_ajax.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/zq.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/common.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/jquery.cookie.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/top.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/tip.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/login.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/down.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/search.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/newmail.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/searchtype.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/user/regist.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/zxs_solor/detail.js?v=5.7.8"></script> <script type="text/javascript" src="https://www.zhangqiaokeyan.com/statistics/static/pagecollection.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/tj.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/sse.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/pushbaidu.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/common/history.js"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/util/cookie.js?v=5.7.8"></script> <script type="text/javascript" src="https://cdn.zhangqiaokeyan.com/js/weipu/weipu.js?v=5.7.8"></script> </body> <script> $(function(){ var weiPuStatus = getCookie('WeiPuStatus'); if(weiPuStatus){ tipWeiPuStatus(weiPuStatus); delCookie('WeiPuStatus'); } getFacetKeywordVoInId(); var sourcetype = $("#sourcetype").val(); var inyn_provide_service_level = $("#inyn_provide_service_level").val(); if((sourcetype ==1||sourcetype==4)&&inyn_provide_service_level!=4){ getJournal(); } }) </script> </html>