Sustained Release of Drugs Dispersed in Polymer Nanoparticles

摘要

About two-thirds of the products utilized in the pharmaceutical industry are in the form of particulate solids.Controlled release as an effective means of delivery of these products to target tissues remains a significant challenge.Herein,we describe the use of supercritical carbon dioxide as an antisolvent for the formation of nanoparticles that comprise biologically active therapeutics dispersed in a biodegradable polymer.