Facile Preparation of Complex Protein Architectures with Sub-100-nm Resolution on Surfaces

摘要

Proteins on surfaces play a ubiquitous and central role in host responses to implanted biomedical devices and in biotechno-logical applications,including in vitro surface-based diagnostic assays and cell-culture supports.In many cases,complex biological functionality results from the interplay of multiple types of proteins:for example,in immune responses involving antigen-presenting cells,in bone regeneration,and in cell adhesion.