Self-Assembly of 1,3,5-Benzer.etricarboxylic Acids (Trimesic Acids) and Several Analogues in the Solid State

摘要

The design of organic compounds thi'.t crystallize in a predictable way remains a contemporary challenge to chemists. Particular attention has recently focused on the rationaldesion of clathrates that may be useful in separations or catalysis. Hydrogen bonding can be useful in this regard because it is a moderately directional iniermolecular interaction that may control short-range packing. Ideally, each functional group or set of hexagonal petworks, respectively. However, channels or cavities arenot present as a result of extensive interueneniration. In the case of 2, the "chicken-wire" networks of trimesic acid mol-ecuies are pleated and the 14 A holes are filled by a mutual triple catenation. Herein we describe the results from ttiree differentapproaches to break the interpcnetration of the trimesic acid lattice to give cavity clathrates. The results bear on the issue of whether the hydrogen bonding of carboxylic acids, and by extension, related functional groups can be used to reliably control the structure of crystals.