OBJECTIVE: This article is a primer in conducting an imaging-guided percutaneous renal ablation program based on the clinical experience of three institutions. CONCLUSION: Imaging-guided percutaneous ablation is becoming a viable alternative to surgery for the management of locally confined renal cell carcinoma. Conducting a successful renal tumor ablation program includes understanding the treatment options for early-stage renal cell carcinoma, selecting the appropriate patients, understanding the procedural techniques, and organizing a comprehensive follow-up.
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