Feasibility of proton FLASH effect tested by zebrafish embryo irradiation

Beyreuther Elke; Brand Michael; Hans Stefan; Hideghety Katalin; Karsch Leonhard; Lessmann Elisabeth; Schuerer Michael; Szabo Emilia Rita; Pawelke Jorg

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Feasibility of proton FLASH effect tested by zebrafish embryo irradiation

机译：斑马鱼胚辐射测试质子闪光效果的可行性

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Background and purpose: Motivated by first animal trials showing the normal tissue protecting effect of electron and photon Flash irradiation, i.e. at mean dose rates of 100 Gy/s and higher, relative to conventional beam delivery over minutes the feasibility of proton Flash should be assessed.

机译：背景和目的：通过第一动物试验的激励，显示电子和光子闪光照射的正常组织保护作用，即在100 GY / s的平均剂量率和更高的情况下，相对于传统的光束输送在几分钟内应评估质子闪光的可行性。

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来源
《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2019年第2019期|共5页
作者
Beyreuther Elke; Brand Michael; Hans Stefan; Hideghety Katalin; Karsch Leonhard; Lessmann Elisabeth; Schuerer Michael; Szabo Emilia Rita; Pawelke Jorg;
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作者单位

Helmholtz Zentrum Dresden Rossendorf Inst Radiat Phys Dresden Germany;

Tech Univ Dresden DFG Ctr Regenerat Therapies Dresden CRTD CMCB Dresden Germany;

Tech Univ Dresden DFG Ctr Regenerat Therapies Dresden CRTD CMCB Dresden Germany;

ELI HU Nonprofit Ltd Attosecond Light Pulse Source Szeged Hungary;

Helmholtz Zentrum Dresden Rossendorf Inst Radiat Phys Dresden Germany;

Helmholtz Zentrum Dresden Rossendorf Inst Radiat Phys Dresden Germany;

Natl Ctr Tumor Dis NCT Heidelberg Germany;

Helmholtz Zentrum Dresden Rossendorf Inst Radiat Phys Dresden Germany;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Proton Flash effect; Proton beam therapy; Normal tissue toxicity; Zebrafish embryo;

机译：质子闪光效果;质子束治疗;正常组织毒性;斑马鱼胚胎;

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专利

1. Feasibility of proton FLASH effect tested by zebrafish embryo irradiation [J] . Beyreuther Elke, Brand Michael, Hans Stefan, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2019,第期

机译：斑马鱼胚辐射测试质子闪光效果的可行性
2. Triphasic Low-dose Response in Zebrafish Embryos Irradiated by Microbeam Protons [J] . Emily Hoi Wa Yum, Kwan Ngok Yu, Masakazu Oikawa, Journal of radiation research . 2012,第3期

机译：质子束辐照斑马鱼胚胎中的三相低剂量响应
3. Some properties of the signals involved in unirradiated zebrafish embryos rescuing alpha-particle irradiated zebrafish embryos [J] . Kong E. Y., Choi V. W. Y., Cheng S. H., International Journal of Radiation Biology: Covering the Physical, Chemical, Biological, and Medical Effects of Ionizing and Non-ionizing Radiations . 2014,第12期

机译：营救α粒子辐照的斑马鱼胚胎的未辐照斑马鱼胚胎所涉及信号的某些特性
4. Automatic Segmentation and Quantitative Analysis of Irradiated Zebrafish Embryos [C] . Melinda Katona, Tunde Tokes, Emilia Rita Szabo, International Symposium on Computational Modeling of Objects Presented in Images . 2019

机译：辐照斑马鱼胚胎的自动分割和定量分析
5. Microstructure Evolution and TEM in situ Mechanical Testing of Proton Irradiated Nanocrystalline Copper Tantalum Alloy [D] . Patki, Priyam 2018

机译：质子辐照纳米晶铜钽合金的组织演变与透射电镜原位力学测试
6. Ion Prostate Irradiation (IPI) – a pilot study to establish the safety and feasibility of primary hypofractionated irradiation of the prostate with protons and carbon ions in a raster scan technique [O] . Gregor Habl, Gencay Hatiboglu, Lutz Edler, 2014

机译：离子前列腺照射（IPI）–一项初步研究以光栅扫描技术确定质子和碳离子对前列腺的一次次分割照射的安全性和可行性
7. Triphasic Low-dose Response in Zebrafish Embryos Irradiated by Microbeam Protons [O] . Viann Wing, Yan Choi, Emily Hoi, 2016

机译：微束质子辐照斑马鱼胚胎的三相低剂量反应

Feasibility of proton FLASH effect tested by zebrafish embryo irradiation

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