1, 8-Naphthalimide-based fluorescent sensor with highly selective and sensitive detection of Zn2+ in aqueous solution and living cells

摘要

A new 4-amino-1,8-naphthalimide-based fluorescent sensor, with iminoethoxyacetic acid and iminopicolinic acid as receptor, was developed and applied successfully to image Zn2+ in living cells. Under physiological pH conditions, it demonstrates high selectivity and sensitivity for sensing Zn2+ with about 30-fold enhancement in aqueous solution, with a characteristic emission band of 4-amino-1,8-naphthalimide with a green color centered at 550 nm.