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Mfsd2a Is Not Involved in the Iron Metabolism

机译:MFSD2A不参与铁代谢

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Background and Aims: Food frequency questionnaires (FFQ) have been widely used in epidemiologic studies since 1990s, but instruments need to be validated. The aim of this work was to create and assess the validity and reproducibility of an interview administered FFQ to be used in a Mexican women's bone health cohort study, located in Monterrey city, Mexico. Methods: Validation of FFQ formed by 11 food groups and 136 food and beverage items was performed on 40-65-year-old Mexican women (n = 200) by applying 2 FFQ (test method) and six 24-h dietary recalls (24hR, reference method; 1 per season on weekdays and 2 on weekends). Pearson correlation coefficient was calculated of both logs, transformed intakes and energy-adjusted nutrient intakes based on the residual method, and intraclass correlation coefficients were calculated. Results: The relative validity of FFQ against the average of six 24hR for intakes of energy, macronutrients, cholesterol, water, vitamins and minerals required for bone metabolism such as vitamin D, calcium, magnesium, phosphorus were obtained. Pearson coefficients of correlation show significance (p < 0.05) for the validity, 0.244-0.820 and 0.258-0.794, for energy-unadjusted and adjusted data, respectively. Reproducibility coefficients range 0.186-0.810 for energy-unadjusted data and 0.174-0.597 for energy-adjusted data. Most nutrients showed lower than 5% of misclassification. Conclusion: The designed 136-item FFQ shows acceptable validity and reproducibility, and it is useful to be applied on 40-65-year-old Mexican women for the estimation of nutrient intakes in epidemiological studies.
机译:背景和宗旨:自20世纪90年代以来,食品频率问卷(FFQ)已广泛用于流行病学研究,但需要验证仪器。这项工作的目的是创造和评估采访的有效性和可重复性,采访的采访,以便在墨西哥蒙特雷市的墨西哥妇女骨骼健康队列研究中使用。方法:通过应用2个FFQ(测试方法)和六个24小时饮食召回(24小时,参考方法;平日和周末每季1个。基于残余方法计算了Pearson相关系数,基于残留方法计算了日志,转化的摄氏性摄入和能量调整后的营养摄入量,并计算了脑内相关系数。结果:对骨代谢所需的能量,常规营养素,胆固醇,水,维生素和矿物质所需的六24小时平均相对有效性,获得维生素D,钙,镁,磷等含量。 Pearson相关系数显示有效性,0.244-0.820和0.258-0.794分别显示有效性(P <0.05),分别用于能量 - 不调整和调整后的数据。用于能量 - 不调整的数据的再现性系数范围为0.186-0.810,用于能量调整数据的0.174-0.597。大多数营养素显示出低于分类的5%。结论:设计的136件FFQ显示了可接受的有效性和再现性,适用于40-65岁的墨西哥妇女进行流行病学研究中的营养摄入量估算。

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