No Guarantees with Johne's Disease: Use of common and novel diagnostic methods

摘要

Keep the purpose of testing in mind when choosing Johne's disease (JD) diagnostics.The usefulness of current JD diagnostics increases with frequency of testing.Inclusion of young stock and calves in testing strategies is recommended.Novel JD diagnostics will come from pathogenomic methods to detect characteristic gene expression, protein biomarkers, metabolites, lipids and shifts in the gut microbiome during Mycobacterium avium subsp. paratuberculosis infection.