首页> 外文期刊>Acta Neurochirurgica >Neurophysiological examination combined with functional intraoperative navigation using TMS in patients with brain tumor near the central region-a pilot study
【24h】

Neurophysiological examination combined with functional intraoperative navigation using TMS in patients with brain tumor near the central region-a pilot study

机译:神经生理学检查与中央区域脑肿瘤患者的功能性术中导航结合功能术中导航 - 试验研究

获取原文
获取原文并翻译 | 示例
获取外文期刊封面目录资料

摘要

Objective Feasibility and value of non-invasive transcranial magnetic brain stimulation (TMS MAGVENTURE (R) MagPro R30 Denmark) for preoperative diagnosis and surgical planning of brain tumor operations in everyday clinical practice. Methods A prospective monocentric study was conducted, which included preoperative neurological and electrophysiological examination, TMS, and display of functional data in the navigation system (LOCALITE (R) TMS Navigator Germany). During surgery, the TMS data were correlated with the intraoperative monitoring (IOM). Twenty-four hours to 96 h and after at least 3 months, follow-ups with neurological, electrophysiological examinations and TMS stimulation were performed. Results Twenty-five patients with tumors in or near by the primary motor cortex region were included in the study. Twenty-one patients completed preoperative and first postoperative TMS and the neurological examination. Eight of 21 patients showed slight worsening of primary motor cortex function, 8 patients had an unchanged state, and 4 patients showed an improvement early after surgery. The changes of the electrophysiological examination like significant delay of the latency and/or reduced amplitudes matched well with the postoperative neurological outcome: if patients showed a worsening of the SEP's and MEP's, the postoperative results revealed deterioration. Conclusion A preoperatively performed TMS using the MAGVENTURE (R) MagPro R30 and the LOCALITE (R) TMS Navigator could be established in our clinical daily practice and allowed a safe and reliable mapping of the primary motor cortex in order to minimize the risk of postoperative neurological deficits and improve the neurological outcome of the patients.
机译:非侵入性经颅磁性脑刺激的客观可行性和价值(TMS Magventure(R)Magpro R30丹麦)在日常临床实践中术前诊断和脑肿瘤作用的术前诊断和手术规划。方法进行前瞻性单眼性研究,包括术前神经和电生理学检查,TMS和导航系统中功能数据的显示(地区(R)TMS Navigator德国)。在手术过程中,TMS数据与术中监测(IOM)相关。二十四小时至96小时,经过至少3个月后,进行了神经学,电生理检查和TMS刺激的随访。结果初级电机皮质地区肿瘤或接近肿瘤患者均纳入该研究。二十一名患者完成术前和首次术后TMS和神经系统检查。八个患者中有八个表现出初级电机皮质功能的轻微恶化,8例患者具有不变状态,4名患者手术早期均显示出改善。电生理学检查的变化如潜水和/或降低幅度的显着延迟与术后神经政治结果相匹配:如果患者表现出患病和MEP的恶化,术后结果显示出恶化。结论在我们的临床日常实践中可以建立使用MAGVENTURE(R)MAGPRO R30和地区(R)MAGPRO R30和地区(R)TMS导航仪的术前进行的TMS,并允许初级电机皮质的安全可靠映射,以尽量减少术后神经系统的风险赤字和改善患者的神经源性结果。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号