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Crystal texture recognition system based on image analysis for the analysis of agglomerates

机译:基于图像分析的晶体纹理识别系统分析附聚物

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摘要

In the process of chemical production and biopharmaceutical, with the complex reaction, the products will overlap or adhere to each other. Effectively distinguishing the overlap and adhesion of crystals is of great significance for the statistics of different morphological characteristics such as the number and size of crystals. This paper proposes a crystal texture recognition system based on image analysis, which mainly includes image preprocessing, feature extraction and texture classification. Firstly, the crystal images are pre-processed to eliminate the influence of water droplets, particle shadows and uneven illumination. Secondly, the Improved-Basic Gray Level Aura matrix (I-BGLAM) is used to extract texture features of the crystals to determine the focus state of crystals. Finally, the texture features are classified by back propagation neural network (BPNN) to effectively distinguish agglomerates and pseudo-agglomerates. The case study and experimental results of cooling crystallization of 1-glutamic acid show that the texture recognition system can effectively distinguish the adhesion and overlap of crystals, and effectively analyze the agglomerates, and has good experimental accuracy.
机译:在化学生产和生物制药的过程中,随着复杂的反应,产品将彼此重叠或粘附。有效地区分晶体的重叠和粘附性对于不同形态特征的统计数据具有重要意义,例如晶体的数量和尺寸。本文提出了一种基于图像分析的晶体纹理识别系统,主要包括图像预处理,特征提取和纹理分类。首先,预处理晶体图像以消除水滴,粒子阴影和不均匀照明的影响。其次,用于提取晶体的纹理特征的改进的基本灰度水平矩阵(I-Bglam)以确定晶体的焦点状态。最后,纹理特征由后传播神经网络(BPNN)分类,以有效地区分附聚物和伪粘聚物。 1-谷氨酸冷却结晶的情况研究和实验结果表明,纹理识别系统可以有效地区分晶体的粘附性和重叠,并有效地分析附聚物,具有良好的实验精度。

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