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首页> 外文期刊>The Journal of Thoracic and Cardiovascular Surgery >Survival and reoperation after valve-sparing root replacement and root repair in acute type A dissection
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Survival and reoperation after valve-sparing root replacement and root repair in acute type A dissection

机译:阀门缩减根替代和根系急性型解剖后存活和重新组合

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摘要

ObjectiveOptimal treatment of the dissected root in type A dissection is still controversial. Valve-sparing techniques offer the advantage of better valve performance compared with mechanical valves or bioprostheses. The role of the different valve-preserving methods—root repair and replacement—needs further evaluation. MethodsFollow-up data (median follow-up, 11.4?years; 95% confidence interval [CI], 10.1-12.7; range, 0-22.1?years) of 179 patients with acute type A dissection and root involvement, who underwent a valve-sparing root replacement using reimplantation (n?=?44) or remodeling (n?=?39) or a valve-sparing root repair (n?=?96) between 1993 and 2017 were analyzed with respect to survival and reoperation. ResultsMedian age of patients with reimplantation was 56.9 (range, 20.2-78), with remodeling 62.6 (range, 31-79.1), and with valve-sparing root repair 64.5 (range, 31-89.6) years. Thirty-day mortality for these groups was 15.9%, 15.4%, and 12.5% (P?=?.829), late mortality at 15?years was 43.2% (95% CI, 28.1-66.5), 36.7% (95% CI, 19.7-68.1), and 36.5% (95% CI, 23.0-57.9;P?=?.504). Risk factors for overall mortality were age, connective tissue disease, total arch replacement, surgical time, cross-clamp time, circulatory arrest, and the reimplantation technique. Cumulative incidence of reoperation at 15?years was 13.4% (95% CI, 2.1-24.7), 20% (95% CI, 6.3-33.6), and 13.3% (95% CI, 4.8-21.7;P?=?.565), respectively. ConclusionsWith the different conditions in each group in this study on patients with acute type A dissection the valve-preserving root repair technique has similar long-term rates of survival and reoperation compared with root replacement techniques, underlining its usefulness as a less complex and even faster surgical technique if individually indicated.
机译:对解剖根的OperiesOptimal治疗A型解剖仍然存在争议。阀门制备技术提供了与机械阀或生物原理相比更好的阀门性能的优势。不同阀门保存方法的作用 - 根修复和更换 - 需要进一步的评估。方法方法(中位后续,11.4岁; 95%置信区间[CI],10.1-12.7;范围,0-22.1岁,0-22.1岁)急性型患者的解剖和根部受累,谁经历了阀门在1993年至2017年期间,使用重新实现(n?=α44)或重塑(n?=Δ39)或重塑(n?=Δ39)或瓣膜备件(n?=Δ96)的重新置换。结果媒体患者的年龄是56.9(范围,20.2-78),重塑62.6(范围,31-79.1),阀门备件根修复64.5(范围,31-89.6)岁。这些群体的30天死亡率为15.9%,15.4%和12.5%(P?= _ 829),晚期死亡率为15?岁以下(95%CI,28.1-66.5),36.7%(95%) CI,19.7-68.1)和36.5%(95%CI,23.0-57.9; p?= 504)。总体死亡率的危险因素是年龄,结缔组织疾病,总拱形替代,手术时间,交叉钳时间,循环停滞和再植入技术。 15岁的累积发病率为15?年为13.4%(95%CI,2.1-24.7),20%(95%CI,6.3-33.6)和13.3%(95%CI,4.8-21.7; P?=? 565)分别。结论在本研究中对急性型患者进行了不同条件的结论,阀门保存的根系修复技术与根替代技术相比具有类似的生存和再生的长期存活率,因此其有用性作为更不重要的复杂性,甚至更快地下调单独指示的外科技术。

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