Structural characterization and cytotoxic evaluation of Cu(II), Co(II) and Ni(II) complexes with herbicide 4-chloro-2-methylphenoxyacetic acid

摘要

The purpose of our research was to obtain and characterize Cu(II), Co(II) and Ni(II) complexes with herbicide 4-chloro-2-methylphenoxyacetic acid (MCPA). The structural characterization of compounds in their powder form was based on various laboratory as well as synchrotron X-ray spectroscopic methods, magnetic measurements and atomistic calculations. The anhydrous [Cu(MCPA)(2)](n) complex exhibits a distorted square-planar geometry. [Co(MCPA)(2)(H2O)(4)]center dot H2O and [Ni(MCPA)(2)(H2O)(4)]center dot H2O complexes have octahedral molecular geometry with two MCPA anions acting as monodentate ligands. The X-ray crystal structure analysis performed for Cu(II) complex after its recrystallization from N,N-dimethylformamide solution showed the formation of dinuclear complex with solvent molecules included in the coordination sphere of Cu(II).