A 2D Graphical Representation of DNA Sequence Based on Dual Nucleotides and Its Application

摘要

From the perspective of the neighboring dual nucleotides, we introduce a novel 2D graphical representation of DNA sequences based on the magic circle, which correspond to 16 dual nucleotides. So, we can reduce a DNA sequence into a plot set in two-dimensional space and get a two-component vector relatively to the introduced covariance matrix. The utility of our approach can be illustrated by the examination of similarities/dissimilarities among the complete coding sequences of beta-globin gene belonging to 11 species. (C) 2008 Wiley Periodicals, Inc. Int J Quantum Chem 109: 948-958, 2009