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Fast weighted centroid algorithm for single particle localization near the information limit

机译:信息极限附近单粒子定位的快速加权质心算法

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摘要

A simple weighting scheme that enhances the localization precision of center of mass calculations for radially symmetric intensity distributions is presented. The algorithm effectively removes the biasing that is common in such center of mass calculations. Localization precision compares favorably with other localization algorithms used in super-resolution microscopy and particle tracking, while significantly reducing the processing time and memory usage. We expect that the algorithm presented will be of significant utility when fast computationally lightweight particle localization or tracking is desired. (C) 2015 Optical Society of America
机译:提出了一种简单的加权方案,可以提高径向对称强度分布的质心计算的定位精度。该算法有效地消除了这种质心计算中常见的偏差。定位精度与超分辨率显微镜和粒子跟踪中使用的其他定位算法相比具有优势,同时显着减少了处理时间和内存使用量。我们期望,当需要快速计算轻量级的粒子定位或跟踪时,提出的算法将具有重要的用途。 (C)2015年美国眼镜学会

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