Catalytic Silylations of Alcohols: Turning Simple Protecting-Group Strategies into Powerful Enantioselective Synthetic Methods

摘要

In recent years, remarkable progress has been made in the enantioselective silylation of alcohols. Owing to the successful site- and stereoselective functionalization of hydroxy groups, silyl ether formations have evolved from being a simple reaction for functional-group protection into a powerful enantioselective process. In this Minireview, we highlight important recent findings in this emerging field.