Metal-Containing Carbonyl Ylides: Versatile Reactants in Catalytic Enantioselective Cascade Reactions

摘要

Catalytic asymmetric cascade reactions represent one of the most powerful and efficient methods for the rapid assembly of biologically active and complex chiral molecules from simple substrates. In this context, the discovery of new strategies through exploration of new reagents, reactive intermediates, and catalytic modes is extremely important in the search for more efficient and stereoselective cascade processes. In particular, the identification of highly reactive intermediates and reaction design provide a fruitful platform for the development of new cascade reactions. In situ generated transition-metal-containing carbonyl ylides have recently emerged as a unique type of versatile agent having a range of applications in various cascade reactions.