Synthesis of (±)-Tetrapetalone A-Me Aglycon

摘要

The first synthesis of (±)-tetrapetalone A-Me agly-con is described. Key bond-forming reactionsinclude Nazarov cyclization, a ring-closing metathesis promoted with complete diastereoselectivity by a chiral molybdenum-based complex, tandem conjugate reduction/intramolecular aldol cyclization, and oxidative dearomatization.