TH Measurements on logP, logD and Kinetic Solubility Accelerates Early Drug Discovery Research

摘要

Current medicinal chemistry is under pressure to accelerate the outcome of research results. Early determination of as much data as possible from new potential drugs is crucial to fulfill this difficult target. A broad knowledge of the properties of all compounds involved in a research project helps the scientists to make the right decision which lead structures they should follow. Zinsser Analytic has developed a sample preparation system that can prepare a complete set of HPLC samples for an exact measurement for kinetic solubility, logP and logD just using a tiny amount of 0.3 μmol.