Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures

摘要

Structural DNA nanotechnology, which includes DNA origami, enables the rapid production of self-assembled nanostructures. One of the key features of this technology is that fully addressable nanoarchitectures of various shapes and geometries are easily designed and constructed. By taking advantage of their addressable nature, DNA nanostructures have been used as scaffolds for the site-directed assembly of functional entities, such as small molecules and nanoparti-cles.