Achieving Enantioselectivity with Chiral Cyclopeetadienylrhodium Complexes

摘要

A significant number of interesting otherwise hard-to-accomplish transformations can be catalyzed by half-sandwich complexes of transition metals, especially by complexes of late transition metals with a single cyclopentadienyl (Cp) or pentamethylcyclopentadienyl (Cp~*) ligand. While it is deceptively easy to conceive of and prepare chiral half-sandwich complexes, there are only few examples of late-transition-metal complexes that have been used successfully as enantio-selective catalysts. Recently, two different strategies have been employed to introduce chirality to rhodium Cp complexes, and their application as enantioselective catalysts for the formation of dihydroisoquinolones from benzamides and olefins has been demonstrated.