Reagent-Installed Capsule Network: Selective TMocarbamoylation of Aromatic Amines in Crystals with Preinstalled CH3NCS

摘要

Porous coordination networks have recently served as crystalline molecular flasks in which chemical reactions occur between incoming reagents and preinstalled substrates within the pores. Since the substrates are in most cases covalently or noncovalently fixed on the network framework, the products cannot be isolated unless the complex is demolished. With a view to practical applications in organic synthesis, we had the idea of "reagent-installed porous networks" in which common organic substrates are converted to desired products by simply passing them through the pores. Such reagent-installed networks are particularly useful if troublesome reagents (e.g., highly volatile, unstable, toxic, or explosive ones) are stably preinstalled.