The Triple Role of Fluoride Ions in Palladiunn-Catalyzei Seznki-Miyaura Reactions: Unprecedented Transmetalation from [ArPdFL2] Complexes

摘要

Palladium-catalyzed Suzuki-Miyaura reactions between aryl boronic acids (Ar'B(OH)2) and aryl halides (ArX) to generate ArAr' require a base, such as hydroxide, carbonate, or fluoride. The mechanism of the reaction has been thoroughly established for cases in which the base employed is OH~- associated with nBu4N~+, an innocent counter cation (Scheme 1).