A-T Base Pairs are More Stable Than G-C Base Pairs in a Hyiratei Ionic Liquid

摘要

The canonical DNA structure is a B-form duplex consisting of Watson-Crick base pairs. In physiologically relevant buffered solutions, G-C base pairs are more stable than A-T base pairs. This stability difference affects the formation of local and long-range DNA structures. DNAs have enormous potential in the fields of nanobiotechnology and biomedical technology because single DNA strands can recognize and hybridize with complementary sequences through highly specific base-pairing interactions.