Gold(I)-Catalyzed Enantioselective Intramolecular Dehydrative Amination of Allylic Alcohols with Carbamates

摘要

The transition-metal-catalyzed enantioselective amination of allylic esters and carbonates represents one of the most well-established routes to chiral, nonracemic allylic amines. With the potential to condense synthetic sequences and reduce waste streams, the dehydrative amination of allylic alcohols as a route to enantiomerically enriched allylic amines has gained considerable interest.