Chemo-and Regioselectiye Direct Hydroxylation of Arenes with Hydrogen Peroxide Catalyzed by a Divanadium-Substituted PhosphotungstateD

摘要

Phenols with one or more functional groups are valuable organic intermediates related to resins, plastics, pharmaceuticals, and agrochemicals in the chemical industry. Most of these phenols are industrially produced by multistep processes. Therefore, the direct catalytic hydroxylation of arenes to phenols with green oxidants, such as H2O2, N2O, and O2, in combination with reductants' has attracted much attention. Whereas the catalytic oxidation of benzene to phenol has been extensively investigated, little is known about the selective direct hydroxylation of substituted derivatives.