Practical Synthetic Organic Chemistry

摘要

The raison d'etre of this unique book, as stated by Caron in the introduction, is the question that he raised in writing a review on C-O oxidations: "how does one sort through this incredible wealth of information" on standard methodologies, i.e., how to separate the good from the bad and from the "don't try this". The result is a compilation of proven methodologies of value to practicing synthetic chemists. The authors are all enthusiastic Pfizer chemists (apart from two exceptions with regard to their affiliation, not their enthusiasm). The chapters describe how to select conditions to test out first for a given transformation with the experienced eye of a med or process chemist, to highlight to scale-up procedures, and to make the book modern (literature > 1980). The result is a refreshing book which, as a hard copy and not an e-book, should be on the shelf of every practicing synthetic chemist.