High-Pressure (+)-Sucrose Polymorph

摘要

With the exponential rise in interest in the fundamental, commercial, and intellectual-property importance of crystal forms, the late Walter McCrone's provocative statement regarding the propensity for the formation of polymorphs is often cited: "It is at least this author's opinion that every compound has different polymorphic forms and that, in general, the number of forms known for each compound is proportional to the time and money spent in research on that compound." (italics in original). In response to McCrone, the lack of evidence for more than one crystal form of two very common, indeed paradigmatic and often crystallized compounds, sucrose and naphthalene, has been frequently cited.