Indirect Cation-Flow Method: Flash Generation of Alkoxycarbenium Ions and Studies on the Stability of Glycosyl Cations

摘要

Organic cations such as alkoxycarbenium ions and N-acyliminium ions are believed to be unstable and transient in common organic solvents and are usually generated in the presence of nucleophiles. In 1999, we developed a method for the generation and accumulation of highly reactive carbocations in solution in the absence of a nucleophile, based on low-temperature electrochemical oxidation. This method is called the cation-pool method.