Allyl-, Allenyl-, and Propargyl-Transfer Reactions through Cleavage of C-C Bonds Catalyzed by an N-Heterocyclic Carbene/Copper Complex: Synthesis of Multisubstituted Pyrroles

摘要

Development of efficient methods for transition-metal-catalyzed selective cleavage of C-C bonds and their application has been a challenging subject of modern organic synthesis. Recently, our research group and others have developed transition-metal-catalyzed retro-allylation of homoallyl alcohols as a C-C bond-cleavage strategy and thus have succeeded in the generation and use of allylmetals under mild conditions.