ipso-Nitration of Arenes

摘要

Aromatic nitro compounds are key synthons in the preparation of many dyes, plastics, perfumes, explosives, and pharmaceuticals. The electrophilic nitration of arenes, one of the most extensively studied organic reactions, results in mixtures of isomeric nitrated products. Since nitrating agents are also good oxidants, the nitrated compounds are often accompanied by oxidation products. Therefore, the development of mild and regioselective nitration methods is of substantial practical interest.