Nickel-Catalyzed Regio-and Enantioselective Annulation Reactions of 1,2,3,4-Benzothiatriazine-1,1(2H)-dioxides with Allenes

摘要

Transition metal complexes promote various annulation reactions, which provide efficient methods for the synthesis of heterocyclic molecules. Such reactions often involve heteroatom-containing metalacycles as the key intermediate, and unsaturated organic compounds are incorporated into heterocyclic skeletons through migratory insertion and reductive elimination. It has been shown that heterocyclic compounds, such as triazoles, phthalimides, phthalic anhydride, and isatoic anhydride serve as the precursor to heteroatom-containing metalacycles through oxidative addition to a low-valent transition metal, and the extrusion of gaseous molecules like N2, CO, and CO2.