Synthesis of Polyarylated Methanes through Cross-Coupling of Xricarbonylchromium-Activated Benzyllithiums

摘要

Polyaryl ated methanes are attracting considerable attention due to their growing importance in developing medicinal agents for cancer and vascular disease, as well as in leuco dye precursors, photochromic agents, and applications in materials science. Most syntheses of polyarylmethanes involve Friedel-Crafts-type (F-C) electrophilic aromatic substitution reactions, although there are some limited exceptions.