Regio-and Stereoselective Generation of Alkenylindiuin Compounds from Indium Tribromide, Alkynes, and Ketene Silyl Acetals

摘要

The synthesis of alkenylmetals by the Lewis acid promoted addition of organometallic compounds to alkynes is an important process in organic chemistry because of the application of this class of compounds in coupling reactions. Despite extensive investigation of addition reactions using alkyl, allyl, alkenyl, and aryl nucleophiles,the use of heteroatom-containing organometallic compounds has rarely been used because a coordinative heteroatom disturbs the weak interaction between an alkyne and a Lewis acid.