Gold- or Platinum-Catalyzed Synthesis of Sulfur Heterocycles: Access to Sulfur Ylides without Using Sacrificial Functionality

摘要

Sulfur ylides are potent reactive units which are utilized in synthetic chemistry for a variety of powerful carbon-carbon and carbon-heteroatom bond-forming reactions. The classical preparation of ylides depend on the use of "sacrificial functionality": a leaving group is displaced by a sulfide with subsequent regioselective deprotonation of the resulting sulfonium salt [Eq. (1)] ; or a sulfide is treated with a metal carbene, which is formed by the decomposition of a diazo compound with loss of molecular nitrogen [Eq. (2)] .