A Selective Fluoroionophore Based on BODIPY-functionalized Magnetie Silica Nanoparticles: Removal of Pb~(~(~(2+)))from Human Blood

摘要

Since heavy metal ions can cause severe risks for human health and the environment,methods for the facile preparation of fluorescence receptors with high selectivity and sensitivity for heavy metal ions have received much attention.Among the known heavy metal ions,Pb~(2+)is one of the most dangerous,causing adverse health effects from lead exposure,particularly in children.A variety of symptoms have been attributed to lead poisoning,including abdominal pain and vomiting.The accumulation of Pb~(2+)in the body leads to many serious human afflictions,including muscle paralysis,mental confusion,memory loss,and anemia,suggesting that Pb~(2+)affects multiple targets in vivo.Plausible molecular targets of lead include calcium-and zinc-binding proteins which control cell signaling and gene expression,respectively.Thus,it is important to develop a safe and effective procedure to detect and remove lead from the body after toxic lead contamination.