Methods for the Incorporation of Carbon-11 To Generate Radiopharmaceuticals for PET Imaging

摘要

Positron emission tomography (PET) imaging is an exciting and rapidly growing area of research in which short-lived radionuclides, such as carbon-11 and fluorine-18, are generated in a cyclotron and used to label small molecules. The resulting 'radiopharmaceuticals' find widespread application in the noninvasive examination of biochemical processes in living human subjects (Figure 1).