Radicals and Transition-Metal Catalysis: An Alliance Par Excellence to Increase Reactivity and Selectivity in Organic Chemistry

摘要

Only a decade ago, a review by Zard was titled: "Riding the tiger: Using degeneracy to tame wild radical reactions" . This perception of radical reactions being wild and hard to control is linked to the short lifetime of radicals and the widely varying kinetics of the individual radical reaction steps. Thanks to the ground-breaking studies by Ingold, Beckwith, Fischer, and Newcomb, the kinetics of radical reactions are known today.