Highly Substituted Furo[3,4-d][1,2]oxazines: Gold-Catalyzed Regiospecific and Diastereoselective 1,3-Dipolar Cycloaddition of 2-(1-Alkynyl)-2-alken-1-ones with Nitrones

摘要

Heterocyclic structures are core components of many natural products and man-made synthetic drugs. The design and synthesis of novel heterocyclic compounds with high efficiency is, therefore, highly desirable. 1,3-Dipolar cycloaddition reactions, which can provide rapid access to heterocyclic compounds in a convergent and efficient manner, have attracted the interest of many chemists.