Tetrameric Iridium Hydride-Rich Clusters Formed under Hydrogenation Conditions

摘要

Asymmetric hydrogenation using iridium catalysts has been recognized as an important alternative to rhodium catalysis in recent years, because it enables the creation of a new stereogenic center without reliance on polar functionality in the substrate. Previous study of Ir hydrogenations provided significant insights into the mechanism, and underscored that an important deactivation process involves the formation of catalytically inactive trimers.