Enantioselective Synthesis of the Central Ring System of Lomaiviticin A in the Form of an Unusually Stable Cyclic Hydrate

摘要

The lomaiviticin family of natural products are potent cytotoxic molecules with remarkable C_2-symmetric structures(Scheme 1).They were isolated from a strain of actino-mycetes,Micromonospora lomaivitiensis,which was itself