Ditryptophan Conjugation Triggers Conversion of Biotin Fibers into Soft Spherical Structures

摘要

Molecular self-assembly is a ubiquitous theme in natural systems where constituent building blocks are recruited following precise pairing patterns,to reveal an array of hierarchical architectures that are primarily supported by noncovalent interactions.The functional role of such structures in nature can be judged from the action of self-assembled actin filaments,which are crucial for morphogenesis and cellular movement,self-organization of mitotic spindles during cell division,and the construction of complex viral capsids,to name but a few.Inspiration derived from natural systems and natural components is increasingly being realized as a rich source of materials which imitate biological structures and function.