H/D Exchange at Aromatic and Heteroaromatic Hydrocarbons Using D2O as the Deuterium Source and Ruthenium Dihydrogen Complexes as the Catalyst

摘要

Hydrogen/deuterium exchange processes are powerful methods to evaluate the potential of a catalyst for the cleavage and formation of a C-H bond. The isotopic exchange reactions can also be of synthetic value, as deuterated and tritiated compounds are used for NMR spectroscopy, for medicinal research, and for drug discovery processes. Furthermore, deuterated polymers have been evaluated for organic light emitting diodes (OLEDs) and are used in optical communication systems. Therefore, there is increasing interest in mild and selective catalytic H/D exchange processes from both fundamental and application-oriented viewpoints.