Semi-synthesis of 2-deoxo- and 3-epi-paraherquamide A.

Lee BH; m.pnu.com; Clothier MF; Johnson SS

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Semi-synthesis of 2-deoxo- and 3-epi-paraherquamide A.

机译：半合成2-deoxo-和3-epi-paraherquamide A.

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2-Deoxo- and 3-epi-paraherquamide A were synthesized from paraherquamide A. 2-Deoxoparaherquamide A has good activity against HC and TC in our jird model comparable to the parent compound, while 3-epi-paraherquamide A showed no activity.

机译：从对乙酰氨基甲酰胺A合成了2-Deoxo-和3-epi-对乙酰氨基甲酰胺A。在我们的Jird模型中，2-Deoxo对乙酰氨基甲酰胺A对HC和TC的活性与母体化合物相当，而3-epi-对乙酰氨基甲酰胺A没有活性。

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《Bioorganic and Medicinal Chemistry Letters》 |2001年第4期|共2页
作者
Lee BH; m.pnu.com; Clothier MF; Johnson SS;
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正文语种 eng
中图分类药学;生物化学;
关键词
Anthelmintics; Indolizines; Spiro Compounds; paraherquamide; 抗蠕虫药; 吲哚嗪类; 螺环化合物;

机译：Anthelmintics;Indolizines;Spiro Compounds;paraherquamide;抗蠕虫药;吲哚嗪类;螺环化合物;

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机译：半合成2-deoxo-和3-epi-paraherquamide A.
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Semi-synthesis of 2-deoxo- and 3-epi-paraherquamide A.

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