A hybrid between the antifungal azole eberconazole and the alkaloid onychine.

摘要

The 9-imidazolylazafluorene 3, a hybrid between the antifungal azole eberconazole and the alkaloid onychine, was prepared from onychine in two steps. This product shows moderate antifungal activity, but, in contrast to other azoles, is not an inhibitor of ergosterol biosynthesis.