Hepatitis B virus DNA viral load determination in hepatitis B surface antigen-negative Swiss blood donors

摘要

BackgroundNucleic acid test (NAT) hepatitisB virus (HBV) screening for all blood donations with a sensitivity limit of 25IU/mL in the individual donation is mandatory in Switzerland since 2009. The aims of the two studies were to define the percentage of antibody to hepatitisB core antigen (anti-HBc) or anti-HBc and antibody to hepatitisB surface antigen (anti-HBs)-positive donors bearing HBV DNA and to gather HBV viral load data on HBV NAT yields during the routine screening since the introduction of the HBV NAT.