Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis.

Biljana Musicki; Trinity J Bivalacqua; Hunter C Champion; Arthur L Burnett

首页> 外文期刊>The journal of sexual medicine >Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis.

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Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis.

机译：西地那非可促进转基因镰状细胞小鼠阴茎中的eNOS活化并抑制NADPH氧化酶。

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Our findings that sildenafil enhances eNOS activation and inhibits NADPH oxidase function in the sickle cell mouse penis offers a vasculoprotective molecular basis for the therapeutic effect of sildenafil in the penis in association with SCD.

机译：我们的发现西地那非可增强镰状细胞小鼠阴茎中eNOS的激活并抑制NADPH氧化酶功能，为西地那非与SCD结合治疗阴茎中的治疗作用提供了血管保护分子基础。

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《The journal of sexual medicine》 |2014年第2期|共7页
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Biljana Musicki; Trinity J Bivalacqua; Hunter C Champion; Arthur L Burnett;
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正文语种 eng
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1. Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis. [J] . Biljana Musicki, Trinity J Bivalacqua, Hunter C Champion, The journal of sexual medicine . 2014,第2期

机译：西地那非可促进转基因镰状细胞小鼠阴茎中的eNOS活化并抑制NADPH氧化酶。
2. Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon. [J] . Kamizato M, Nishida K, Masuda Journal of gastroenterology . 2009,第12期

机译：白介素10抑制人结肠上皮细胞和小鼠结肠中干扰素γ和肿瘤坏死因子α刺激NADPH氧化酶1的激活。
3. Interleukin 10 inhibits interferon γ- and tumor necrosis factor α-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon [J] . Mai Kamizato, Kensei Nishida, Kiyoshi Masuda, Journal of Gastroenterology . 2009,第12期

机译：白介素10抑制人结肠上皮细胞和小鼠结肠中干扰素γ和肿瘤坏死因子α刺激NADPH氧化酶1的激活
4. Inhibitors of diverse metabolic steps cause increased apoptosis in deoxyadenosine-resistantmouse leukemia L1210 cells that lack p53 expression: convergence at caspase-3 activation [C] . Ann H. Cory, Caroline C. Edwards, Jennifer G. Hall, International Symposium on Regulation of Enzyme Activity and Synthesis in Normal and Neoplastic Tissues . 2003

机译：不同代谢步骤的抑制剂导致缺乏p53表达的脱氧腺苷抵抗疗效中的细胞凋亡增加：Caspase-3活化的收敛性
5. The role of iNKT cells and adenosine A2A receptor activation in the pathogenesis of pulmonary dysfunction in sickle cell disease [D] . Wallace, Kori L. 2009

机译：iNKT细胞和腺苷A2A受体激活在镰状细胞病肺功能障碍发病机理中的作用
6. Sildenafil Promotes eNOS Activation and Inhibits NADPH Oxidase in the Transgenic Sickle Cell Mouse Penis [O] . Biljana Musicki, Trinity J. Bivalacqua, Hunter C. Champion, -1

机译：西地那非可促进转基因镰状细胞小鼠阴茎中的eNOS活化并抑制NADPH氧化酶。
7. Sildenafil Promotes eNOS Activation and Inhibits NADPH Oxidase in the Transgenic Sickle Cell Mouse Penis [O] . Biljana Musicki, Trinity J. Bivalacqua, Hunter C. Champion, 2014

机译：西地那非促进ENOS活化并抑制转基因镰状细胞小鼠阴茎中的NADPH氧化酶

Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis.

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