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首页> 外文期刊>The Journal of Infectious Diseases >Age-Related Immune Dysfunction in Health and in Human Immunodeficiency Virus (HIV) Disease: Association of Age and HIV Infection with Naive CD8+ Cell Depletion, Reduced Expression of CD28 on CD8+ Cells, and Reduced Thymic Volumes.
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Age-Related Immune Dysfunction in Health and in Human Immunodeficiency Virus (HIV) Disease: Association of Age and HIV Infection with Naive CD8+ Cell Depletion, Reduced Expression of CD28 on CD8+ Cells, and Reduced Thymic Volumes.

机译:在健康和人类免疫缺陷病毒(HIV)疾病中与年龄相关的免疫功能障碍:年龄和HIV感染与朴素的CD8 +细胞耗竭,CD8 +细胞上CD28的表达减少以及胸腺体积减少相关。

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摘要

Older age is a strong predictor of accelerated human immunodeficiency virus (HIV) disease progression. We investigated the possible immunologic basis of this interaction by comparing older (>/=45 years) and younger (
机译:老年人是加速人类免疫缺陷病毒(HIV)疾病发展的有力预测指标。我们通过比较年龄较大的(> / = 45岁)和年龄较小的(

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