The effects of dietary change on serum cholesterol

摘要

Cholesterol is undoubtedly an important cause of coronary heart disease, which adds to the risk associated with other major causes such as smol~(-1) g and hypertension (Kannel et al. 1986). The British are a high-cholesterol population, with more than40% of middle-aged adults having a serum cholesterol higher than 6-5 mmol/1 (Shaper & Pocock, 1985; Tunstall-Pedoe, 1988; Thompson, 1989a). If attainable, cholesterol reduction will prevent coronary heart disease Every 1% reduction in cholesterol reduces coronary events by about 2.5%, so that a 10% reduction in cholesterol will result in a worthwhile 25% coronary prevention (Marmot, 1994) Given these facts the case for lowering cholesterol seems overwhelming.